Blunted response to hypercapnia: synonymous with depressed respiratory drive?
نویسنده
چکیده
The pathophysiology of failure to wean from mechanical ventilation consists of depressed central respiratory drive, impaired respiratory mechanics, respiratory muscle weakness, increased load, impaired gas exchange, and compromised cardiovascular performance. Among patients with weaning failure, depressed central respiratory drive occurs in only a small portion (approximately 10%),1 whereas most patients demonstrate augmented drive with the development of progressive ventilatory failure.2
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ورودعنوان ژورنال:
- Respiratory care
دوره 53 8 شماره
صفحات -
تاریخ انتشار 2008